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1

Mechanism of Activation of -D-2'-Deoxy-2'-Fluoro-2'-C-Methylcytidine and Inhibition of Hepatitis C Virus NS5B RNA Polymerase

Murakami, E., Bao, H., Ramesh, M., McBrayer, T. R., Whitaker, T., Micolochick Steuer, H. M., Schinazi, R. F., Stuyver, L. J., Obikhod, A., Otto, M. J., Furman, P. A.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2007

Language:

english

File:

PDF, 205 KB

english, 2007

2

ChemInform Abstract: Synthesis and anti-HIV Evaluation of 3′-Triazolo Nucleosides.

Vincent Roy, Aleksandr Obikhod, Hong-Wang Zhang, Steven J. Coats, Brian D. Herman, Nicolas Sluis-Cremer, Luigi A. Agrofoglio, Raymond F. Schinazi

Journal:

Year:

2012

File:

PDF, 23 KB

2012

3

Synthesis and evaluation of 3′-azido-2′,3′-dideoxypurine nucleosides as inhibitors of human immunodeficiency virus

Hong-wang Zhang, Steven J. Coats, Lavanya Bondada, Franck Amblard, Mervi Detorio, Ghazia Asif, Emilie Fromentin, Sarah Solomon, Aleksandr Obikhod, Tony Whitaker, Nicolas Sluis-Cremer, John W. Mellors,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 307 KB

english, 2010

4

Synthesis, antiviral activity, and stability of nucleoside analogs containing tricyclic bases

Franck Amblard, Emilie Fromentin, Mervi Detorio, Alexander Obikhod, Kimberly L. Rapp, Tamara R. McBrayer, Tony Whitaker, Steven J. Coats, Raymond F. Schinazi

Journal:

European Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 250 KB

english, 2009

5

Simultaneous quantification of 9-(β-d-1,3-dioxolan-4-yl)guanine, Amdoxovir and Zidovudine in human plasma by liquid chromatography–tandem mass spectrometric assay

Emilie Fromentin, Ghazia Asif, Aleksandr Obikhod, Selwyn J. Hurwitz, Raymond F. Schinazi

Journal:

Journal of Chromatography B

Year:

2009

Language:

english

File:

PDF, 446 KB

english, 2009

6

The use of modifiers in preparing transparent polycaproamide monofilaments

T. P. Semenova, V. I. Isaeva, V. F. Lednik, V. V. Obikhod, V. P. Kabanov

Journal:

Fibre Chemistry

Year:

1983

Language:

english

File:

PDF, 381 KB

english, 1983

7

Singularities of Toric Manifolds

Journal:

Ukrainian Mathematical Journal

Year:

2001

Language:

english

File:

PDF, 81 KB

english, 2001

8

Synthesis, antiviral activity, cytotoxicity and cellular pharmacology of l-3′-azido-2′,3′-dideoxypurine nucleosides

Hong-wang Zhang, Mervi Detorio, Brian D. Herman, Sarah Solomon, Leda Bassit, James H. Nettles, Aleksandr Obikhod, Si-jia Tao, John W. Mellors, Nicolas Sluis-Cremer, Steven J. Coats, Raymond F. Schinaz

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 962 KB

english, 2011

9

Evaluation of Single and Combination Therapies with Tenofovir Disoproxil Fumarate and Emtricitabine In Vitro and in a Robust Mouse Model Supporting High Levels of Hepatitis B Virus Replication

Schinazi, R. F., Bassit, L., Clayton, M. M., Sun, B., Kohler, J. J., Obikhod, A., Arzumanyan, A., Feitelson, M. A.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2012

Language:

english

File:

PDF, 706 KB

english, 2012

10

Synthesis and Anti-HIV Evaluation of 3′-Triazolo Nucleosides

Roy, Vincent, Obikhod, Aleksandr, Zhang, Hong-Wang, Coats, Steven J., Herman, Brian D., Sluis-Cremer, Nicolas, Agrofoglio, Luigi A., Schinazi, Raymond F.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2011

Language:

english

File:

PDF, 231 KB

english, 2011

11

Simultaneous Quantification of Intracellular Natural and Antiretroviral Nucleosides and Nucleotides by Liquid Chromatography−Tandem Mass Spectrometry

Fromentin, Emilie, Gavegnano, Christina, Obikhod, Aleksandr, Schinazi, Raymond F.

Journal:

Analytical Chemistry

Year:

2010

Language:

english

File:

PDF, 642 KB

english, 2010

12

Mechanisms Associated with HIV-1 Resistance to Acyclovir by the V75I Mutation in Reverse Transcriptase

Tchesnokov, E. P., Obikhod, A., Massud, I., Lisco, A., Vanpouille, C., Brichacek, B., Balzarini, J., McGuigan, C., Derudas, M., Margolis, L., Schinazi, R. F., Gotte, M.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 2.04 MB

english, 2009

13

Delayed Chain Termination Protects the Anti-hepatitis B Virus Drug Entecavir from Excision by HIV-1 Reverse Transcriptase

Tchesnokov, E. P., Obikhod, A., Schinazi, R. F., Gotte, M.

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 1.12 MB

english, 2008

14

Pharmacokinetics of the Anti-Human Immunodeficiency Virus Agent 1-( -D-Dioxolane)Thymine in Rhesus Monkeys

Asif, G., Hurwitz, S. J., Obikhod, A., Delinsky, D., Narayanasamy, J., Chu, C. K., McClure, H. M., Schinazi, R. F.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2007

Language:

english

File:

PDF, 118 KB

english, 2007

15

Pre-steady-state Kinetic Studies Establish Entecavir 5'-Triphosphate as a Substrate for HIV-1 Reverse Transcriptase

Domaoal, R. A., McMahon, M., Thio, C. L., Bailey, C. M., Tirado-Rives, J., Obikhod, A., Detorio, M., Rapp, K. L., Siliciano, R. F., Schinazi, R. F., Anderson, K. S.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 374 KB

english, 2007

16

Cellular Pharmacology of 9-( -D-1,3-dioxolan-4-yl) Guanine and its Lack of Drug Interactions with Zidovudine in Primary Human Lymphocytes

Hernandez-Santiago, B. I., Obikhod, A., Fromentin, E., Hurwitz, S. J., Schinazi, R. F.

Journal:

Antiviral Chemistry & Chemotherapy

Year:

2007

Language:

english

File:

PDF, 125 KB

english, 2007

17

Engineering of a Chimeric RB69 DNA Polymerase Sensitive to Drugs Targeting the Cytomegalovirus Enzyme

Tchesnokov, E. P., Obikhod, A., Schinazi, R. F., Gotte, M.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 1.70 MB

english, 2009

18

Substrate mimicry: HIV-1 reverse transcriptase recognizes 6-modified-3'-azido-2',3'-dideoxyguanosine-5'-triphosphates as adenosine analogs

Herman, B. D., Schinazi, R. F., Zhang, H.-w., Nettles, J. H., Stanton, R., Detorio, M., Obikhod, A., Pradere, U., Coats, S. J., Mellors, J. W., Sluis-Cremer, N.

Journal:

Nucleic Acids Research

Year:

2012

Language:

english

File:

PDF, 5.66 MB

english, 2012

19

Telbivudine exerts no antiviral activity against HIV-1 in vitro and in humans

van Maarseveen, Noortje M, Wensing, Annemarie MJ, de Jong, Dorien, Beilhartz, Greg L, Obikhod, Aleksandr, Tao, Sijia, Pingen, Marieke, Arends, Joop E, Hoepelman, Andy IM, Schinazi, Raymond F, Götte, M

Journal:

Antiviral Therapy

Year:

2011

Language:

english

File:

PDF, 351 KB

english, 2011

20

Searches for Massive Graviton Resonances at the LHC

Obikhod, T. V., Petrenko, I. A.

Journal:

Advances in High Energy Physics

Year:

2018

Language:

english

File:

PDF, 1.90 MB

english, 2018

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